Last update
4/3/2026

Overview

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
USERS' SCORE
Good
Based on 2 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil (Seed) providing:
1300 mg
***
Linoleic Acid
949 mg
***
Gamma-Linolenic Acid
117 mg
***
📅 Last updated:

Top Medical Research Studies

8
Evening primrose oil shows promise
We analyzed how different types of dietary fats might influence breast cancer growth. In our study, we used athymic mice with human breast cancer cells and supplemented their diets with evening primrose oil and fish oil, while others received olive oil or a standard diet without essential fatty acids.

We found that the tumors in the mice receiving evening primrose oil were significantly smaller compared to those on a standard diet — suggesting that increasing essential fatty acids could play a beneficial role in managing breast cancer.
Read More
7
Evening primrose oil enhances tamoxifen
We explored the potential of evening primrose oil (EPO) to enhance the effects of tamoxifen—an established breast cancer treatment. In laboratory tests using human breast cancer cell lines, EPO showed promising results, working alongside tamoxifen to encourage cancer cell death and stop cell growth.

While our findings suggest that EPO can improve tamoxifen's anticancer abilities, more research is needed to fully understand its impact on breast cancer treatment in patients.
Read More
5
Evening primrose oil shows limited effects
We conducted a randomized, double-blind, controlled trial to explore the effects of fish oil and evening primrose oil (EPO) on breast cancer patients undergoing chemotherapy. Over 12 weeks, participants received either the oil supplements or a placebo.

While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.

Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.
Read More

Most Useful Reviews

9
Cycle regulation
1 people found this helpful
I noticed my cycle normalised in just a month and my breast size increased. I’m satisfied and have reordered!
Read More
6
Rare breast pain
I take evening primrose oil with other supplements for treating mastopathy. I’ve noticed less intense and infrequent breast pain. It’s essential to balance omega-3 with omega-6.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.7
  • All Researches
8
Evening primrose oil shows promise
We analyzed how different types of dietary fats might influence breast cancer growth. In our study, we used athymic mice with human breast cancer cells and supplemented their diets with evening primrose oil and fish oil, while others received olive oil or a standard diet without essential fatty acids.

We found that the tumors in the mice receiving evening primrose oil were significantly smaller compared to those on a standard diet — suggesting that increasing essential fatty acids could play a beneficial role in managing breast cancer.
Read More
7
Evening primrose oil enhances tamoxifen
We explored the potential of evening primrose oil (EPO) to enhance the effects of tamoxifen—an established breast cancer treatment. In laboratory tests using human breast cancer cell lines, EPO showed promising results, working alongside tamoxifen to encourage cancer cell death and stop cell growth.

While our findings suggest that EPO can improve tamoxifen's anticancer abilities, more research is needed to fully understand its impact on breast cancer treatment in patients.
Read More
5
Evening primrose oil shows limited effects
We conducted a randomized, double-blind, controlled trial to explore the effects of fish oil and evening primrose oil (EPO) on breast cancer patients undergoing chemotherapy. Over 12 weeks, participants received either the oil supplements or a placebo.

While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.

Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Cycle regulation
1 people found this helpful
I noticed my cycle normalised in just a month and my breast size increased. I’m satisfied and have reordered!
Read More
6
Rare breast pain
I take evening primrose oil with other supplements for treating mastopathy. I’ve noticed less intense and infrequent breast pain. It’s essential to balance omega-3 with omega-6.
Read More

Frequently Asked Questions

9
Cycle regulation
1 people found this helpful
I noticed my cycle normalised in just a month and my breast size increased. I’m satisfied and have reordered!
5
Evening primrose oil shows limited effects
We conducted a randomized, double-blind, controlled trial to explore the effects of fish oil and evening primrose oil (EPO) on breast cancer patients undergoing chemotherapy. Over 12 weeks, participants received either the oil supplements or a placebo.

While we noted improvements in fatty acid profiles in the treatment group, the study showed no significant changes in inflammatory markers between the two groups. Despite a decrease in IL-6 levels in the intervention group, there was no major benefit observed overall.

Ultimately, our findings suggest that while this supplementation can help with lipid metabolism, it does not deliver significant anti-inflammatory effects for breast cancer patients undergoing chemotherapy.
7
Evening primrose oil enhances tamoxifen
We explored the potential of evening primrose oil (EPO) to enhance the effects of tamoxifen—an established breast cancer treatment. In laboratory tests using human breast cancer cell lines, EPO showed promising results, working alongside tamoxifen to encourage cancer cell death and stop cell growth.

While our findings suggest that EPO can improve tamoxifen's anticancer abilities, more research is needed to fully understand its impact on breast cancer treatment in patients.
8
Evening primrose oil shows promise
We analyzed how different types of dietary fats might influence breast cancer growth. In our study, we used athymic mice with human breast cancer cells and supplemented their diets with evening primrose oil and fish oil, while others received olive oil or a standard diet without essential fatty acids.

We found that the tumors in the mice receiving evening primrose oil were significantly smaller compared to those on a standard diet — suggesting that increasing essential fatty acids could play a beneficial role in managing breast cancer.

References

  1. Arsic A, Krstic P, Paunovic M, Nedovic J, Jakovljevic V, et al. Anti-inflammatory effect of combining fish oil and evening primrose oil supplementation on breast cancer patients undergoing chemotherapy: a randomized placebo-controlled trial. Sci Rep. 2023;13:6449. 10.1038/s41598-023-28411-8
  2. Abd-Alhaseeb MM, Massoud SM, Elsayed F, Omran GA, Salahuddin A. Evening Primrose Oil Enhances Tamoxifen's Anticancer Activity against Breast Cancer Cells by Inducing Apoptosis, Inhibiting Angiogenesis, and Arresting the Cell Cycle. Molecules. 2022;27. 10.3390/molecules27082391
  3. Pritchard GA, Jones DL, Mansel RE. Lipids in breast carcinogenesis. Br J Surg. 1989;76:1069. PubMed
Data last updated:
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